my wife has beeb undergoing investigation by an allegist and respirologist for respiratory difficulty for the last 3 years. Her condition is progressivly getting worse. multiple test for allergies have proven negative, xray,CT scan of chest, throat shows no abnormalities, PFT normal, methacholine challange negative. Bloodwork normal except for slight anemia. She has been trialled on a wide selection of nsaids, steriods, alppha/beta agonists inhaled and ingested with no change in sensitivity.
She is a 45 yo fit with no ongoing medical problems except her difficulty with airway sensitivity.
Her symptoms include respiratory distress, severe headache, excess mucus production to the point where she chokes or as she describes it a drowning feeling which she has difficulty breathing through. she battles to cough and expells copious amounts of clear phlem.
Her triggers are diverse. Cold to warm changes, warm to cold changes scents such as pine, cedar, vinegar, perfume paint, solvents, dust, marker, smoke, sawdust, musk, exhaust fumes, insect reppelant, new plastics, petrochemicals. laughing to hard with bring on excess mucus production as will even moderate exertion.
desperatly looking for any suggestions