I don't see what it would hurt. During those two weeks you wouldn't do much but look at it anyway. The only gamble you would take is if you lost power or had a sprayer clog. If it's new I wouldn't give to much thought to sprayer clog, and if the power goes out you couldn't change much being home anyway.

I would say go for it, since by the end of christmas your kids might have moved on and this is your chance to really get them into growing.

If you start it the day you leave it might be okay for 2 weeks unattended, but my guess would be that it wouldn't go more than a week.

See if you can get someone to check in on it once or twice, just to top off the reservoir.