You'll find excellent info at Harvard.

http://www.hsph.harvard.edu/bedbugs/

Understand you must complete all the steps.

Beyond that, it's likely you'll need help from a professional pest control company.

Here is a link that might be useful: bed bug management info from Harvard

I had bed bugs in Mexico. I don't know how to get rid of them in a bed or home.
We went to the pharmacy in Mexico motioning with our hands in a scratching motion.
They led us to the the dog and flea soap.
My husband and I bathed in it and the bed bugs were gone on our bodies. Hope this helps. Carol